Quantifying the similarity of multiple point processes with application to early diagnosis of Alzheimer's disease from EEG

A novel approach is proposed to quantify the similarity (or “synchrony”) of multiple multi-dimensional point processes. It is based on a generative stochastic model that describes how two or more point processes are related to each other. As an application, the problem of diagnosing Alzheimer's disease (AD) from multi-channel EEG recordings is considered. The proposed method seems to be more sensitive to AD induced perturbations in EEG synchrony than classical similarity measures.