FDG imaging of 1mm tumor with an ultra high resolution animal PET

Recently, we reported an animal semiconductor PET with the spatial resolution of 0.8 mm FWHM within the central 20 mm-diameter of FOV for the purpose of biomedical study using rats and mice. This ultra high spatial resolution was obtained by the use of small CdTe elements of 1.1mm x 1.0 mm x 5 mm. The FOV of this PET is 64 mm in diameter and 26 mm in axis. We applied to observe small tumors in mouse and succeeded to 1 Q obtain [ F]FDG images of mouse mammary carcinoma of ~1mm size.