Improved Liquid Phase Chromatography Separation using Sub-micron Micromachining Technology

While liquid phase chromatography is using macroscopic columns filled with micron scale particles, a major separation enhancement is expected when using perfectly ordered (sub-) micron structures. Therefore an on-wafer chromatograph was fabricated using advanced micromachining technology. The first characterization results are presented and compared to the performance of state-of-the-art macroscopic devices.