A Nanobiosensor Fabricated by Nanoimprinting Technology

A new biosensor with a high sensitivity and a low process cost is presented in this paper. Localized surface plasmon resonance generated inside the nanogrooves was verified to have a high sensitivity and this structure could be produced using a nano imprinting technology which realizes a high reproducibility and a mass-production. The present sensor had five times as high sensitivity as the conventional colloidal localized surface plasmon resonance sensor. And the detection of BSA antigen using the present sensor was attained in this research.