SIMULATION OF THE DIFFUSION IN THE INTERSTITIAL SPACE OF A FIBER PHANTOM

The diffusion in the extra cellular space of brain white matter in vivo can be considered as the analogue of diffusion in porous media and can be studied ex vivo by fiber phantoms with diffusion weighted magnetic resonance imaging. Based on phantom studies and Monte Carlo simulations, the diffusion properties in the interstitial space were studied in the short and long time limit, whereby the effect of the fiber geometry and density was evaluated.