Controlling electrical side effects of cardiac stimulus pulses due to high impedance electrodes

A method of measuring the extracellular voltage field in working cardiac tissue with high impedance sensors immediately after a superthreshold stimulation pulse has been developed. Previously, the stimulus pulse charged the input circuitry of the front-end amplifier with an amplitude much greater than the biological signal desired. To address this problem a blanking period was introduced which disables the amplifiers for the duration of the superthreshold stimulus pulse. As a result of this process, electrical activity can be measured almost immediately after the superthreshold stimulus pulse without distortion.<
>