Abstract:
A simple electronic circuit is proposed as an analog of the excitable membrane. It is based on the Hodgkin-Huxley model and their squid axon voltage clamp data. The simul...Show MoreMetadata
Abstract:
A simple electronic circuit is proposed as an analog of the excitable membrane. It is based on the Hodgkin-Huxley model and their squid axon voltage clamp data. The simulated potassium and sodium conductances are reproduced satisfactorily and the electronic action potentials are very similar to the experimentally recorded ones. Since this analog contains only a few electronic elements, it is small and inexpensive to build. It could be very useful as a means of simulating a wide variety of membrane conductances and different types of action potentials. Also, the simplicity of the circuit makes it an ideal unit to build complex neuron networks.
Published in: IEEE Transactions on Biomedical Engineering ( Volume: BME-19, Issue: 1, January 1972)