Three zone segregation of proteins-a comparison of structures

In our work, we have made two groups of protein structure. One group is for mesophilic proteins, the other is for thermophilic proteins. For each protein under consideration we have collected three to five PDB structures of the same proteins from different organisms. This pdb is called CSR pdb file. For each protein we have one CSR pdb for thermophilic and one for mesophilic. We then structurally aligned the two CSR tiles by the help SPDBV for the comparative study and measuring the RMSD deviation for various aligning regions. Thus from the experimental results and discussion, the low value of RMSD deviation suggests that the particular region of the thermophilic and mesophilic proteins are in good correspondence structural alignment of the proteins.