Enhancing accuracy in magneto-and electroencephalography focal source localization

This paper investigates the origins of localization errors when cortically distributed source approach is applied to magnetoencephalography (MEG) and electroencephalography (EEG) focal source reconstruction problems. It was revealed from simulations that the errors mainly stem from 1)Asymmetric distribution of crosstalk and 2)Large noises at some time slices. To enhance the localization accuracy, a new algorithm named cortical surface scanning (CSS) method is presented. The proposed algorithm was applied to realistic simulations and more accurate and robust source estimates could be obtained.