Three-dimensional motion analysis of mitral valve leaflet in children with congenital heart disease and its clinical significance: a pilot study

This study is to quantitatively evaluate abnormal movement of mitral apparatus (MA) in patient with congenital mitral valve regurgitation using self-designed three dimensional motion analyses software and enable doctors to intuitionistic and "en-face" visualize the mitral valve's movement by using pseudocolor coding of the moving velocity of mitral valve leaflet. Initial evaluation of the software was conducted in 20 children with congenital mitral valve regurgitation (MR) including 10 children with mild MR and 10 children with moderate to severe MR. Results showed that, the moving velocity of the rough zone of mitral valve during systolic phase in children with moderate to severe MR is much high than that in control group. It's indicated that three dimensional motion analysis of mitral valve could emerge to be a new potential useful parameter for evaluation the truly mechanism of MR