Single-cell-based electrophysiological measurement of a topographically controlled neuronal network using agarose architecture with a multi-electrode array

Understanding the indeterminate development of neural networks requires a better understanding of the epigenetic information acquisition processes of neural cells. A main interest in the field of neuroscience is how such information is processed and recorded as plasticity within a network pattern. Also of interest is what might be caused by changes in the network pattern or by changes in the degree of complexity related to network size. One of the best approaches to understanding the meaning of network pattern and size is to analyze the functions of an artificially constructed neural cell network under fully controlled conditions.