Influence of dendritic spines shape changes by learning

The role of dendritic spines in information processing of a neuron is still not clear. But it is known that they change its shape rapidly and fast during learning processes. These effects may be important for storing of information (memory). We show the influence of shape variations on the electrical signal propagation trough dendritic spines by biologically realistic electrical simulation. Basic properties of electrical signal transmission of single spines are estimated and approximated depend on the individual shape. Learning processes to adjust specific electrical properties are discussed and a possible mechanism is introduced.