A 0.18/spl mu/m CMOS 10/sup -6/ lux bioluminescence detection system-on-chip

A chip comprising a 8x16 pseudo-differential pixel array, 128-channel 13b ADC and column-level DSP is fabricated in a 0.18/spl mu/m CMOS process. Detection of 10/sup -6/lux at 30s integration time is achieved via on-chip background subtraction, correlated multiple sampling and averaged 128 13b digitizations/readout. The IC is 25mm/sup 2/ and contains 492k transistors.