A fully electronic DNA sensor with 128 positions and in-pixel A/D conversion

A 16x8 CMOS sensor array for fully electronic DNA detection is presented. Each position contains a complete A/D converter with a dynamic range of five decades. The 3/spl sigma/-homogeneity of the electrical response of the sensor array is better than 6% (10/sup -21/A to 10/sup -7/A). The 28.8mm/sup 2/ IC is fabricated in a 0.5/spl mu/m 2M CMOS process extended to form Au sensors.