3D finite element complex domain numerical models of electric fields in blood and myocardium

The conductance catheter system is a tool to determine left ventricular (LV) volume in vivo. However, the accuracy of this method is limited by three assumptions of the equation to convert conductance to volume: the assumed homogeneity of electric field within LV, myocardium having resistive and not capacitive properties, and assumed constant parallel myocardial conductance. This study investigates weaknesses of these three assumptions. It proposes an equivalent circuit model for mouse LV as well as a calculation method for conductance and capacitance of LV. Furthermore, this study also demonstrates the importance of phase measurement in vivo experiments.