Triple-Band Terahertz Metamaterial Ultra-Sensitive Absorber for Multi-Class Cancer Cell Detection

This study introduces a meticulously optimized, Tri-spectral THz meta-absorber designed for high-resolution spectroscopic interrogation of cancer cell detection. The device architecture employs copper-based square-ring resonators atop a cost-efficient FR-4 dielectric substrate, conFig.d within a multilayer stack to support distinct resonance modes at 0.717, 1.368, and 3.535 THz. Geometric parameter tuning via a genetic algorithm facilitates enhanced field confinement and spectral selectivity, yielding high absorption magnitudes approaching 99.99 %. The absorber exhibits pronounced sensitivity to minute dielectric perturbations, achieving sensitivity to the refractive index peaking at 7357.14 GHz/RIU, alongside elevated quality factors and narrow linewidths. Electromagnetic simulations validate its robustness against angular incidence and mechanical deformation, underscoring its applicability in dynamic or flexible sensing environments. The proposed platform demonstrates strong potential for label-free, noninvasive differentiation of malignant cellular structures, thereby offering a promising modality for next-generation terahertz biosensing in oncological diagnostics.