Advanced Bio-Mimetic Coating of Titanium Implants with Silver Nano Stars: Evaluation of Surface Interactions and Anti-Biofilm Activity

Titanium implants are extensively used in the medical and healthcare industries because of their exceptional mechanical strength and biocompatibility. However, there are still concerns with reducing infection and enhancing implant integration with the surrounding bone tissue. This study reported star like silver nanoparticles and coat them on titanium discs. Polyvinyl and ethylene glycol were used to stabilize the nanostar. Different properties of nanoparticles such as Surface morphology, functional groups, chemical composition, phase and purity, visual characterization, surface charge and stability were characterized by using Scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X ray diffraction, UV-Vis spectroscopy and zeta analysis,. To enhance surface qualities, titanium discs were heated and given alkaline treatments. Simulated body fluid and nanostar-coated discs interacted, and contact angle was measured in order to test biocompatibility. The antibacterial efficacy was evaluated against Staphylococcus aureus and there was a significant decrease in biofilm activity observed on 96 well plate. 7 days and 14 days coated disc shows 80% and 90% inhibition to biofilm and there was a decrease in contact angle of both discs with increasing coating period, and 14 day coated disc shows contact angle of 22° indicating high hydrophilicity that leads to better Osseo integration and biocompatibility.