Enhancing Monophasic Defibrillation Efficacy: A Metaheuristic Approach to Parameter Optimization

Sudden cardiac arrest, frequently triggered by cardiac fibrillation, remains a significant global health concern. Defibrillation is a critical medical procedure that relies on precise electrical pulses to restore normal heart rhythm. To optimize pulse parameters, such as peak voltage and duration, we employ the Differential Evolution algorithm on a monophasic waveform. By utilizing the error between circuit simulation and targeted defibrillation parameters as an objective function, we aim to determine the optimal inductance and capacitance values of the defibrillator circuit. This approach enables the delivery of precisely tailored electrical shocks, potentially improving defibrillation success rates, reducing patient risk, and ultimately, contributing to advancements in cardiac care.