Modeling and Experimental Evaluation of Biomolecules' Behaviors Grafted on the Blood Vessels Microchip Under a Pulsatile Flow

This paper reports on the numerical modeling and experimental evaluation of the behaviors of biomolecules immobilized on the surface of blood vessels on microchip under pulsatile flow conditions, which include velocity profiles of the fluids and shear stress profiles around the biomolecules. Using fluorescent BSA, FITC conjugates mimicking biomolecules, the behaviors of the biomolecules can be optically observed, facilitating the quantitative studies and analysis.