Edge-Enhanced Dilated Residual Attention Network for Multimodal Medical Image Fusion

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning methods, particularly Convolutional Neural Networks (CNNs) and Transformers, have significantly advanced fusion performance, some of the existing CNN-based methods fall short in capturing fine-grained multiscale and edge features, leading to suboptimal feature integration. Transformer-based models, on the other hand, are computationally intensive in both the training and fusion stages, making them impractical for real-time clinical use. Moreover, the clinical application of fused images remains unexplored. This work proposes a novel CNN-based architecture that addresses these limitations by introducing a Dilated Residual Attention Network Module for effective multiscale feature extraction, coupled with a gradient operator to enhance edge detail learning. To ensure fast and efficient fusion, we present a parameter-free fusion strategy based on the nuclear norm of softmax weights, which requires no additional computations during training or inference. Extensive experiments demonstrate that our approach outperforms various baseline methods in visual quality and fusion speed, making it a possible practical solution for real-world clinical applications. Code will be released at https://github.com/simonZhou86/endran.