RadiomixNet: Integrating Radiomics and Feature Extraction for Advanced Pneumonia Diagnosis

The research outlines a workflow for medical image analysis and disease diagnosis through radiomics feature extraction. The dataset, consisting of chest X-ray images, was pre-processed using techniques such as denoising, resizing, and enhancement to ensure uniformity and high image quality. Advanced texture analysis methods, including Gray Level Size Zone Matrix, Gray Level Co-Occurrence Matrix, Gray Level Dependence Matrix and, Gray Level Run Length Matrix were employed to extract radiomics features. Power Spectral Density analysis using Burg, Yule Walker, and Welch techniques further enriched the understanding of frequency characteristics within the radiomics feature matrices, uncovering patterns vital for precise predictions. Diverse classifiers, including Bernoulli Naïve Bayes, Random Subspace Boost, Quadratic Discriminant, and Gradient Boosting, were employed to classify test X-rays. The performance of these classifiers was evaluated using metrics such as Cohen’s Kappa, Accuracy, Matthews Correlation Coefficient, Sensitivity, Youden’s Index, Specificity, Log Loss, and Brier Score. Among these, Gradient Boosting demonstrated superior performance across all feature sets, achieving a Cohen’s Kappa of 0.93, MCC of 0.88, Youden’s Index of 0.82, and a Log Loss of 0.27.