Effect Of Mimosa Pudica Linn Extract On Excision Wound Healing

Mimosa pudica Linn has many therapeutic benefits due to its phytocompounds with scavenging radicals that hinder the wound healing process, such as phenolics and flavonoids. This study aimed to estimate the total phenolic content (TPC) and total flavonoid content (TFC) of leaf and root extract from a mixed solvent of water and ethanol. The results showed that in water and ethanol with a ratio of $1: 1$, both leaf and root extracts had the highest TPC and TFC (179,1 $\mathrm{mgGAE} / \mathrm{g}$ ew and $28.6 \mathrm{mgQE} / \mathrm{g}$ ew for leaf extract, and 370.9 $\mathrm{mgGAE} / \mathrm{g}$ ew and $41.7 \mathrm{mgQE} / \mathrm{g}$ ew for root extract, respectively). Moreover, the wound healing study of the two extracts above on excision wounds exhibited that root extract had a higher effect, especially, at the concentration of 1% in vaseline. This sample showed the fastest wound healing rate (8.3%), and the shortest epithelization time (14.2 days) compared to others.