Dual Micro-trench Photonic Crystal Fiber based Surface Plasmon Resonance sensor for early diagnosis of Anemia

This work proposes a photonic crystal fiber(PCF)-based surface plasmon resonance(SPR) sensor tailored for comprehensive refractive index sensing in early anemia diagnosis. The sensor features two air holes of different diameters and includes a micro-trench in the PCF, which is coated with gold on its outer surface. The finite element method is utilized to evaluate how changes in the refractive index affect the performance of the sensor in determining anemia conditions. By carefully adjusting various trench geometric parameters and using COMSOL Multiphysics for simulation, the sensor shows enhanced performance metrics, achieving a significant maximum wavelength sensitivity of 2620 nm/RIU and amplitude sensitivity of 177 (1/RIU). Engineered to operate within the near-infrared spectrum, this biosensor can detect refractive index range of 1.32 to 1.36, a spectrum encompassing the refractive index variations associated with diverse anemia conditions in blood.