Optical-Magnetic Characterization of IgG and Nanoparticles for Rapid Biosensor Development: Detection of Cardiac Markers and Mycotoxins

This study introduces a novel method for characterizing immunoglobulins G (IgG) and functionalized nanoparticles crucial in biosensor development. Utilizing label-free low-coherence interferometry and magnetic lateral flow immunoassay, the method enables kinetic studies, IgG sorption density quantification, and functional nanoparticle characterization. Demonstrated efficacy in creating highly sensitive assay systems for mycotoxins and cardiovascular biomarkers highlights the method’s potential impact across diverse compounds. With promising results in sensitivity, dynamic range, and analysis time, this approach offers versatility for advancing rapid biosensor systems.