Clinical and immunologic results of photodynamic therapy for HPV-associated cervical diseases

Chlorine E6 photodynamic therapy (PDT) was used to treat 183 patients with HPV-related cervical diseases. The main of this study was to characterize the local immune response during treatment with PDT in patients with persistent HPV infection, LSIL, HSIL and cervical cancer. PDT is able to stimulate antiviral innate immune response, being important to treatment effectiveness.