A Wearable Quantified Approach to Parkinson’s Disease Gait Motor Symptoms

The progressive and complex nature of Parkinson’s disease (PD) may largely benefit from regular and personalised monitoring, which is beyond the current clinical practice and routinely available systems. This paper proposes a simple and effective system to address this issue by using a wearable device to quantify a key PD’s motor symptom - gait impairment - as a proof-of-concept for a future broader approach. In this study, 60 inertial signals were collected from the ankle in 41 PD patients during a clinical standard gait assessment exercise. Each exercise iteration was classified by a specialised neurologist based on the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS). A signal processing and feature extraction pipeline was employed to characterise gait, followed by a statistical analysis of their ability to differentiate between the 5 levels of impairment. The results revealed that 4 of the 8 studied features exhibited high discriminatory power between different severity levels of gait impairment, with statistical significance. The distinguishing capability of these 4 extracted features - gait consistency, rotation angle, mean height and length of steps - holds great promise for the development of a gait severity quantification remote monitoring for PD patients at home or on the move, proving the concept of the usefulness of wearable devices for regular and personalised PD symptom monitoring.