Real-Time Quantitative Detection of Cardiac Function Marker NT-pro BNP Based on Magnetic Relaxation Sensing

A magnetic relaxation method for the quantitative detection of Amino-terminal B-type natriuretic peptide precursor (NT-pro BNP), a marker of cardiac function, is proposed in this paper. Through the efficient binding of magnetic nanoprobes to the target, we established the mapping relationship between the cardiac markers and the magnetic relaxation signal. The detection time of a single sample is within 1 min, which greatly reduces the time of detection compared with the time of about 10 minutes required for other traditional sensors based on electrochemical or optical signals.