Cancer Cell Detection Biosensor Utilizing Dual-Core PCF-Based Surface Plasmon Resonance

Early detection of cancer cells, crucial for improving patient outcomes, is facilitated through internal and external sensing techniques, leveraging photonics technology for precise and reliable detection. These methods offer remarkable sensitivity, selectivity and durability, enhancing the effectiveness of treatment approaches in healthcare. Utilizing a dual-core photonic crystal fiber (PCF) and exploiting the surface plasmon resonance (SPR) effect, the sensor boasts the potential to detect diverse cancer types, including Jurkat, Basal and Hela. Simulated using the Finite Element Method, the sensor leverages gold, coated with protective titanium dioxide, to detect variations in the surrounding medium's refractive index, operating effectively between 1.360 and 1.392. Remarkably, it exhibits the maximum reported sensitivity for wavelength of 10714.29 nm/RIU, showcases a linear sensing response, solidifying its real-world applicability across various cancers. This holistic approach represents a significant advancement in cancer detection technology, holding immense promise for enhanced diagnosis and treatment outcomes. This innovative study unveils a novel optical sensor designed to locate cancerous cells present in the human body.