Development of Molecular-Imprinted Electrochemical Sensor for Linolenic Acid

In this letter, an electrochemical sensor for linolenic acid (ALA) based on molecular imprinting technique was constructed. The screen-printed electrode was used as the substrate electrode. The conductivity of the sensor was increased by modifying gold nanoparticles and ferrocene-carboxylated graphene oxide-carboxylated multiwalled carbon nanotubes complex materials, and molecularly imprinted film was polymerized on the surface of the electrode by electropolymerizing method using polydopamine as the functional monomer and ALA as the template molecule. The sensor shows good linearity in the range of ALA concentration from 1.1 × 10
⁻⁹
mol/L to 1.1 × 10
⁻³
mol/L with a detection limit of 0.031 nM (S/N = 3). This is the first molecularly imprinted polymer-based electrochemical sensor for ALA, and it has great potential in practical applications.