Modulation of Zebrafish Heart Rate by Alternating Magnetic Fields With Frequencies Close to Heart Rhythm | IEEE Journals & Magazine | IEEE Xplore

Modulation of Zebrafish Heart Rate by Alternating Magnetic Fields With Frequencies Close to Heart Rhythm


Schematic diagram of the experimental design used in the present study
Impact Statement:Take-Home Messages •Extremely low-frequency magnetic fields (ELF-MF) up to 100 μT influence physiological processes, including heart function. •We suggested that direct e...Show More

Abstract:

Extremely low-frequency magnetic fields (ELF-MF) up to 100 μT exhibit impacts on physiological processes, including heart function. The mechanisms underlying the influenc...Show More
Impact Statement:
Take-Home Messages •Extremely low-frequency magnetic fields (ELF-MF) up to 100 μT influence physiological processes, including heart function. •We suggested that direct exposure to ELF-MF with a frequency close to the heart rate could entrain oscillatory processes maintaining heart rhythm in zebrafish embryos. •Zebrafish embryos' heart rates, ranging from 1.44 to 3 Hz depending on age, were exposed to ELF-MF with frequencies matching, 10% higher, or lower than the heart rate. •Almost all tested ELF-MF induced an increased heart rate effect (fields with frequencies close to the heart rate did not entrain cardiac contractions), especially pronounced when exposure occurred earlier during ontogenesis. •A significant negative correlation between changes in heart rate and ELF-MF frequency was observed for fields with different intensities.

Abstract:

Extremely low-frequency magnetic fields (ELF-MF) up to 100 μT exhibit impacts on physiological processes, including heart function. The mechanisms underlying the influence of these fields on fish heart rates remain insufficiently explored. We assumed that the direct impact of ELF-MF with a frequency close to the heart rate could entrain oscillatory processes responsible for autonomously maintaining heart rhythm in zebrafish embryos. Embryos' heart rates ranged from 1.44 to 3 Hz depending on age, and ELF-MF with frequencies precisely matched, 10% higher, or lower than the heart rate were applied. Additionally, embryos experienced ELF-MF with amplitudes varying by an order of magnitude. Almost all tested ELF-MF induced an increased heart rate effect. This effect was the most pronounced when the exposure occurred earlier during ontogenesis. Fields with frequencies close to the heart rate did not entrain cardiac contractions in zebrafish embryos. A significant negative correlation between ...
Schematic diagram of the experimental design used in the present study
Page(s): 317 - 324
Date of Publication: 13 May 2024

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