Personalized Adjustment of Near Infrared Spectroscopy Studies Using Fmri Data for Research in Neuroscience

The advantages of functional near infrared spectroscopy (fNIRS) determine the width and perspective usage of this method in functional diagnostics of cerebral blood circulation and functional activity of the brain. The quantitative assessment of the components of neurovascular coupling, such as blood flow autoregulation and the rate of oxygen consumption by brain tissues is of particular interest for modern neuroscience. A methodology for personalized setup of fNIRS studies based on the structural and functional data of a single magnetic resonance scanning is proposed. During the adjustment, the depth of the activated cerebral cortex area, its size and projection on the surface of the head, and the curvature of the surface are estimated. The received data are used for positioning of the optical probe and its geometry adjustment in order to conduct longitudinal fNIRS studies of both patients and healthy subjects with good reproducibility and comparability of the results.