Exploring Risk Factors in PDAC Using System Dynamics

Pancreatic ductal adenocarcinoma (PDAC) is a lethal gastrointestinal cancer prevalent in developing countries with a low survival rate. Early detection remains challenging despite medical advancements. The exact causes of PDAC are unknown; however, genetic, environmental, and lifestyle factors are believed to contribute to this cancer. Modifiable and non-modifiable risk factors like smoking, obesity, gender, and age play a role in PDAC development. System dynamics is utilized to build causal loops, unraveling complex interactions between these factors. Further research is necessary to uncover additional modifiable causes of PDAC. Public health campaigns are essential to raising awareness, and educate about PDAC risks, and pro-moting preventive measures to reduce mortality and morbidity associated with the disease.