Neural and neuro-fuzzy models of toxic action of phenols

The problem of describing the bio-chemical action of different classes of chemical compounds through relations dependent on their structures is known as the quantitative structure-activity relation (QSAR) problem. Development of toxicity models of phenols using neural and neuro-fuzzy models is here proposed. A dataset about the inhibition of growth determined by phenolic compounds to the protozoan ciliate Tetrahymena pyriformis was used to produce QSAR and connectionist models. The results are promising, and suitable for further research.