Revealing Types of Transport Regimes for Organometallic Markers Spreading in a Collagen-Based Brain Parenchyma's Phantom

Here we report the results of an experimental investigation of the ferroin-based liquid marker's spread from a cylindrical channel in a hydrogel's bulk. This physical model simulates the process of delivering organometallic contrast fluid to the brain after penetrating the blood-brain barrier. In addition to the study of the spatiotemporal dynamics by the cross-section profiles of the marker's distribution, the relaxation of the initial concentration is analysed. This analysis argued in favour of a two-stage spread process, which takes the classic diffusion character after some transient time only.