Pertaining analysis of fracture risk in Osteoporotic patients using Machine Learning Techniques

Bone fractures in the spine or hip are the most severe complications of Osteoporosis. Older subjects with Osteoporosis are vulnerable to falls. This paper aims to review the breakthrough in machine learning methods over the past four years in assessing fracture risk in osteoporotic patients. Machine learning is applied in the healthcare and medical field. Machine learning professionals can accurately predict disease onset by analyzing a large amount of data. Osteoporosis is one of the healthcare domains in which new Machine learning and Artificial Intelligence techniques can be implemented. The objective of this research is to give an overview of the recent advancements in machine learning methods in finding out the risk factors for fractures or predicting the onset of disease. A systematic search was conducted in PubMed to get research papers published on Machine learning methods to detect, classify, or predict osteoporosis-related fracture risk. The articles belonging to Fracture prediction and risks (n=14), Osteoporosis classification(n=3), Diagnosis of fracture(n=3), and Predicting length of stay (n=1) were identified. The quality of the articles is assessed. Most articles described the efforts to create the model and showcased excellent results in predicting the risks. Significant limitations were in the form of inadequate data splitting and data validations. More validation studies are needed in various large groups to improve the model. Most of the participants in significant studies were in their initial stage of the disease, and the reproducibility analysis was done with major disease issues.