Multimodal Coherent Raman and Multiphoton Nonlinear Optical Microscopy Reveals Early Risk of Tumour Recurrence After Anticancer Therapy in Human Cells

Recent studies have shown that common anticancer treatments can induce cell senescence rather than death, which is a critical phenotype governing tumour recurrence, dormancy and treatment resistance [1]. This calls for the urgent development of safe, precise, and rapid tools to unveil early evidence of such therapy-induced senescence (TIS).