Raman spectroscopy of serum for cancer detection

Laser induced auto-fluorescence and Raman spectra of serum from cancerous and normal people are measured and analyzed. Three Raman peaks were consistently observed from normal blood serum emission using 488.0 nm and 514.5 nm excitation of an Ar-ion laser, whereas no peak or only slight Raman peaks were detected from the tumorous cases. The content of -carotene in the normal serum is higher than that from the cancerous serum. This result agrees with other reports.