A High Performance Computing Platform for Big Biological Data Analysis

With the rapid progress of high-throughput sequencing projects, biological data is growing exponentially, creating a need for efficient and scalable algorithms and high-performance computing (HPC) platforms for big biological data analysis. However, traditional HPC platforms are inadequate for meeting the demand for rapid data analysis tasks in bioinformatics research. Analyzing biological sequence data is challenging due to its complexity and long computing time. This poses challenges for researchers to gain a deep understanding of biological functions. Thus, this research presents a large-scale biological data analysis platform enabled by an HPC infrastructure for genomic sequencing data and protein structure analysis. This study lists the characteristics of big biological data and traditional computing platforms, provides a reconfigurable HPC platform for biological data analysis applications. A practical case of HPC platforms for big biological data analytics in Taiwan is also presented. By using a reconfigurable HPC platform, the computational bottleneck can be removed, and data analysis can be accelerated. The platform enables researchers to gain profound insights into the deepest biological functions by addressing the challenges of big biological data analysis.