MHL-Net: A Multistage Hierarchical Learning Network for Head and Neck Multiorgan Segmentation

Accurate segmentation of head and neck organs at risk is crucial in radiotherapy. However, the existing methods suffer from incomplete feature mining, insufficient information utilization, and difficulty in simultaneously improving the performance of small and large organ segmentation. In this paper, a multistage hierarchical learning network is designed to fully extract multidimensional features, combined with anatomical prior information and imaging features, using multistage subnetworks to improve the segmentation performance. First, multilevel subnetworks are constructed for primary segmentation, localization, and fine segmentation by dividing organs into two levels—large and small. Different networks both have their own learning focuses and feature reuse and information sharing among each other, which comprehensively improved the segmentation performance of all organs. Second, an anatomical prior probability map and a boundary contour attention mechanism are developed to address the problem of complex anatomical shapes. Prior information and boundary contour features effectively assist in detecting and segmenting special shapes. Finally, a multidimensional combination attention mechanism is proposed to analyze axial, coronal, and sagittal information, capture spatial and channel features, and maximize the use of structural information and semantic features of 3D medical images. Experimental results on several datasets showed that our method was competitive with state-of-the-art methods and improved the segmentation results for multiscale organs.