An application of THz gas high resolution spectroscopy method for investigation of thermal decomposition products of biological liquid (urine) of rats with dysbacteriosis

The thermal decomposition products of urine samples from rats with artificially induced dysbacteriosis were studied in this work by means of terahertz nonstationary gas high resolution spectroscopy. A set of metabolites appeared during thermal decomposition of samples (healthy, with artificially induced dysbacteriosis, with various treatment regimens) was revealed, and the compositions of gaseous products were compared. The presented approach is promising for the development of a non-invasive research method that allows to identify markers that reflect the presence of dysbacteriosis, as well as to assess the impact on the rat’s organism during the therapy.