The Comparative Analysis of Different HD-TES Montages

Transcranial electrical stimulation (TES) as a non-invasive neuromodulation tool has modulatory effects on brain injury recovery and cognitive enhancement. Conventional TES induces a huge individual difference in modulation effects since it can not focus on the specific target. High-Definition TES (HD- TES) has enhanced the targeted focus of TES and could potentially solve the problem. Currently, the design of HD-TES montage divide into two types: HD-4*1 and HD-Ring, yet, the difference between the two montages is unclear. The maximum norm of the electric field (NormE), size, and overlap ratio of stimulation area between two electrode montages were compared using 10 individual head models with the same electrode size. The NormE (R2=0.997, p=0.000) and the stimulation volume (R2=0.974, p=0.000) produced by the two electrode montages showed a high correlation, the stimulation area overlap ratio (min=0.631, max=0.984) was relatively large when the electrodes have the same area, which could help the selection of HD-TES electrode montages during the experiments.