Electrochemotherapy is a clinical therapy that uses voltage pulses to electropore cell membranes. This paper presents the description of an experimental set-up including the design of a prototype of voltage pulses generator for laboratory experiments in electroporation. The prototype has been designed to study the threshold of electric field that allows the cell membrane electroporation increasing...Show More
Electrochemotherapy (ECT) is a local anticancer treatment for superficial tumors which involves the administration of a chemotherapeutic drug followed by short, highvoltage pulses. Incipient clinical experience with breast cancer patients are encouraging, with a local complete response rate ranging from 50 to 90%. However, since many patients present with multiple or widespread metastases, ECT, de...Show More
A multiobjective optimization method is used to design a treatment planning based on electrochemotherapy (ECT). A penalty function technique is coupled to NSGA algorithm in order to identify the constrained Pareto front, so preventing unfeasible solutions.Show More
