The Localization of the Epileptogenic Zone from the Interictal Electroencephalogram

In the case of patients diagnosed with focal epilepsy, to establish a diagnosis and a treatment, it is necessary to know the source area in the patient's brain where the epileptic seizure is generated. In current clinical practice, these areas are detected by invasive methods such as electrocorticogram, combined with magnetic resonance imaging methods, which subject the patient to discomfort during the procedure. The supporting paper proposes the localization of epileptic foci in a more friendly way based on electroencephalographic (EEG) signals acquired non-invasively. The article approaches various models of inverse problems, aiming to achieve a spatial identification of the epileptogenic areas as precisely as possible, then projected on a three-dimensional model of the cortex and tomographic images. The results are compared with those obtained by doctors through invasive methods found in the support database. This analysis aims to classify the methods related to the diagnosis established by the medical personnel.