Visualizing perfusion throughout the cardiac cycle using advanced power Doppler acquisition and filtering methods

Evaluating blood flow in the liver has clinical implications for functional and oncological assessment. Here, we explore visualization of temporally varying power Doppler signals in the 3 vasculature systems in the liver using coded excitation acquisitions and block-wise SVD filtering that mitigate the limitations of poor SNR, spectral overlap, and shorter ensembles. We acquired 2 seconds of data with matched ECG traces, and then evaluated 100 sample ensembles across the ECG trace to assess optimal cardiac phases for forming images. We show that highest CNR and SNR values are obtained from images formed during diastole.