An Enhancement Technology on Fluoroscopy Imaging Using Xray Fluorescence

To enhance the contrast of fluoroscopy in the diagnosis of lung diseases, we use contrast agents containing high atomic number metal elements in fluoroscopy imaging. The metal atom-containing agents can be enriched in the lesion, and the fluoroscopy signal and the fluorescent signal emitted by the metal atoms due to the x-ray fluorescence effect can be detected at the same time during the fluoroscopy. We propose three schemes: pencil beam spot scanning method, cone-beam collimation method and slit scanning method to integrate the two signals and explore the feasibility and enhancement effects by Monte Carlo simulations based on GEANT4.