Nuclear Magnetic Resonance Spectroscopy Application in charterization of Heterocyclic Compounds

NMR was originally developed to check the structure of relatively tiny molecules, but it has since grown in popularity and become a useful technique to find out structure on compounds. NMR can reveal the 3D structures of tiny compounds, high-molecular-weight compound, and delicacy of enzyme processes, all of which can help with drug development.The conventional procedure for the title heterocyclic compound is unsuitable since it necessitates long reaction durations, the use of proprietary and potentially hazardous solvents, and low yield. As a result, we established a simpler and advantageous technique for synthesizing title medication under moderate and environmentally favorable reaction circumstances. Microwave aided organic synthesis is projected to have a broader application in organic synthesis due to its operational simplicity, universality, and efficacy.There is growing attention of eco-friendly chemicals and microwave irradiation technique. This method of synthesis gained reputation in now days due of simplicity and no use of hazardous chemicals. Organic synthesis without hazardous solvent like dioxin or strongly acidic keeps the environment pollution free. When two or more heterocyclic nuclei are combined, the biological profile is generally enhanced. Characterization of all compounds are completed by 1HNMR Spectroscopy by spinning of
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H-nuclei.