A probabilistic approach to the design of microelectrode layouts for neural signal transducers

Neural signal transducers consisting of arrays of microelectrodes fabricated on a substrate are considered. The geometries and spacings of the microelectrodes have a major impact on the characteristics of the neural signals that are obtained. The design of microelectrode layouts that maximize the probability of obtaining easily detectable neural spikes is discussed. It is shown that a selectivity-noise tradeoff exists. A computer simulation is used to quantify this tradeoff.<>