A Distributed Simulation Approach to Integrate AnyLogic and Unity for Virtual Reality Applications: Case of COVID-19 Modelling and Training in a Dialysis Unit

Different heterogeneous simulation components can be integrated to produce a more effective complex global system. The IEEE High-Level Architecture (HLA) is an international standard that promotes interoperability and reusability for distributed simulation (DS). This paper proposes a DS system that integrates an agent-based and discrete-event simulator with a 3D game engine to build virtual reality (VR) applications that replicate real environments. In this case study, AnyLogic is used as an agent-based and discrete event simulator to simulate the process flow and COVID-19 transmission inside the University Health Network dialysis unit, Toronto, Canada. Unity game engine delivers the 3D modelling replicating the real architecture and environment of the dialysis unit. The HLA standard plays a major role in the integration of AnyLogic and Unity to produce a more effective and powerful DS system for VR applications.