Rosette Vanadium Sulfide Nanosheet Spheres-Reduced Graphene Oxide Nanosheets for Ultrasensitive and Selective Detection of Epinephrine

Non-enzymatic voltammetric analysis of epinephrine (EP) was conducted based on three-dimensional rosette vanadium sulfide nanosheet spheres-reduced graphene oxide nanosheets/indium tin oxide (VS
₂
NSSs-RGO/ITO) electrode. The results show that the diameter of VS
₂
NSSs is about
$5~\mu \text{m}$
and the thickness of nanosheet is 200 nm, and the RGO is a transparent sheet structure with some folds. The electrode exhibits an enhanced electrochemical response in EP analyte, which shows a high sensitivity of
$1.39\,\,\mu \text{A}\cdot \mu \text{M}^{-1}$
towards EP (0–
$60~\mu \text{M}$
) and the lowest detection limit obtained is
$0.017~\mu \text{M}$
(S/N = 3). The electrode also exhibits an excellent selectivity, repeatability and stability. The prepared sensor has been successfully applied in real samples and it has a great potential to be used in clinical test.