Analytical Globally-Regularized Estimation Of Effective Scatterer Diameter And Acoustic Concentration in Quantitative Ultrasound

Quantitative ultrasound (QUS) aims at recovering quantitative properties of tissue microstructure by investigating the power spectra of the radio frequency data or statistics of the envelope of the backscattered signal. The accuracy and precision of microstructural properties are necessary for a correct description of tissue microstructure. In this paper, we propose a novel technique to analytically estimate the effective scatterer diameter and the acoustic concentration using simultaneous attenuation compensation. We show that our proposed technique substantially outperforms a recently-proposed, dynamic-programming based method, and is 100 times faster.